According to Dr. Dale Bredesen, author of The End of Alzheimer’s, Alzheimer’s disease is the third leading cause of death in the U.S. and the number one cause of death in the U.K. It is a trillion dollar global problem, one that can potentially bankrupt Medicare. It affects not only the patient, but also family members and caregivers. New research identifies many mechanisms of cause, such as leaky gut (intestinal permeability), chronic inflammation, presence of the APOE4 gene, loss of trophic (hormonal) support and toxin exposure.